artemether/lumefantrine will lessen the level or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

bosentan will lower the level or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

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Propylene glycol toxicity claimed in patients treated with diazepam injection at doses drastically higher than proposed when it was getting used to deal with Liquor withdrawal signs at doses >900 mg/day Propylene glycol toxicity is related to an anion gap metabolic acidosis, serum hyperosmolality, and enhanced lactate

There are actually postmarketing stories of coma and death with coadministration of buprenorphine and benzodiazepines. In several, but not every one of these scenarios, buprenorphine was misused by self-injection. If a benzodiazepine has to be employed for an indication apart from seizures, reduce the benzodiazepine Preliminary dose and cautiously titrate to scientific response.

Compound Use Dysfunction. Diazepam is actually a managed compound and could be misused or cause dependence. Inform your Health care supplier When you have a background of a drug or Liquor ailment. 

diazepam will increase toxicity of oliceridine by Other (see comment). Modify Therapy/Watch Intently. Comment: Anticholinergic medication may well boost hazard of urinary retention and/or critical constipation, here which may bring about paralytic ileus.

Lonafarnib may improve the AUC and peak focus of CYP2C19 substrates. If coadministration unavoidable, check for adverse reactions and reduce the CYP2C19 substrate dose in accordance with its authorised solution labeling.

iloperidone improves amounts of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Iloperidone is usually a time-dependent CYP3A inhibitor and will bring on elevated plasma levels of medicine predominantly removed by CYP3A4.

dexamethasone will lessen the level or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

diazepam will boost the stage or effect of isavuconazonium sulfate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

Keep track of Closely (1)ethinylestradiol will boost the degree or result of diazepam by System: reducing metabolism.

醫學界視苯二氮䓬類藥物較以往常用的巴比妥鹽類藥物更好，因為後者的治療劑量和中毒劑量差距較少（即是稍微過量便容易中毒），且会形成较强的依赖性。過量服用地西泮較不容易引致死亡（不過仍然有人因服用地西泮過量而死亡），但如同時服用其它鎮靜劑或酒類則會增加危險。

lasmiditan, diazepam. Possibly raises consequences of another by sedation. Use Warning/Keep track of. Coadministration of lasmiditan along with other CNS depressant medication, which include Alcoholic beverages haven't been evaluated in medical research. Lasmiditan may possibly induce sedation, along with other cognitive and/or neuropsychiatric adverse reactions.